Azoran 25 Tablet

Description

About Azoran 25 Tablet

Azoran 25 Tablet is used to reduce the pain/inflammation in rheumatoid arthritis conditions and keep the immune system from attacking new transplant organs like kidneys. Besides this, it also treats pain and inflammation in gastrointestinal issues like Crohn’s disease and ulcerative colitis for patients who have undergone a kidney transplant.

Azoran 25 Tablet contains ‘Azathioprine’ that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Azoran 25 Tablet helps stop your body from rejecting a new organ by suppressing your immune system.

Take Azoran 25 Tablet as prescribed. Your doctor will advise you on how often you take Azoran 25 Tablet based on your medical condition. In some cases, you may experience certain common side-effects such as nausea, headaches, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, increase in liver enzymes, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Azoran 25 Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Azoran 25 Tablet if you are pregnant or planning for pregnancy. Azoran 25 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Azoran 25 Tablet should not be given to children as safety and efficacy have not been established. Azoran 25 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Azoran 25 Tablet . While taking Azoran 25 Tablet , do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person who has them, please inform your doctor immediately, as special treatment is required if you have not had these illnesses. Your doctor may advise you to undergo regular blood tests and kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of Azoran 25 Tablet

Treatment of Rheumatoid arthritis, Immunosuppressant therapy after kidney transplant.

Medicinal Benefits

Azoran 25 Tablet contains ‘Azathioprine’, which is an immunosuppressant that works by reducing the function of the cells and causing inflammation in the joint tissues. It reduces pain and inflammation and slows joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Azoran 25 Tablet helps stop your body from rejecting a new organ by suppressing your immune system. Azoran 25 Tablet is also used to treat severe inflammatory diseases of the skin, Crohn’s disease, ulcerative colitis, and some blood disorders.

Directions for Use

Swallow Azoran 25 Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Azoran 25 Tablet

• Nausea
• Headaches
• Vomiting
• Diarrhoea
• Unusual fatigue
• Dizziness
• Headache
• Loss of appetite
• Increase in liver enzymes
• Lowered resistance to infections
• Tingling sensation
• Stomach pain
• Leukopenia (decreased number of white blood cells)
• Sore throat

In-depth Information

Drug Warnings

Do not take Azoran 25 Tablet if you are allergic to any immunosuppressant medicines or Azathioprine. Let your doctor know before using Azoran 25 Tablet if you have liver or kidney problems, serious blood disorders, immune system problems, bone marrow problems, serious infections, immunodeficiency syndrome, or if you have a condition where your body produces too little of a natural chemical called thiopurine methyltransferase (TPMT), received any vaccinations. Do not take Azoran 25 Tablet if you are pregnant or planning for pregnancy as Azoran 25 Tablet is a Pregnancy category risk D medicines which can cause serious congenital disabilities to the unborn baby. Azoran 25 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. While taking Azoran 25 Tablet , do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person having them, please inform your doctor immediately as it requires special treatment if you have not had these illnesses. Azoran 25 Tablet causes dizziness and drowsiness, so drive with caution. Azoran 25 Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Azoran 25 Tablet as it could lead to increased dizziness. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Using Azoran 25 Tablet for a long time can increase your chance of getting certain types of cancer, such as lymphoma (cancer of the spleen, thymus gland, and bone marrow), leukemia (blood cancer), and skin cancer. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Azoran 25 Tablet .

Drug Interactions

Drug-Drug Interaction: Azoran 25 Tablet may have interaction with other immunosuppressant medicines (tacrolimus), anti-gout (allopurinol, oxypurinol, thiopurine), angiotensin-converting enzyme (ACE) inhibitors (benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril), blood thinner (warfarin, phenprocoumon), medicines used to treat inflammation of the bowels (infliximab), medicines used to treat ulcers (cimetidine, olsalazine, mesalazine, sulfasalazine), diuretics (furosemide), medicines used to treat bacterial infections (trimethoprim, sulfamethoxazole), pain killers (indomethacin), medicines used as muscle relaxants (d-tubocurarine, pancuronium, succinylcholine).

Drug-Food Interaction:  Avoid alcohol consumption while taking Azoran 25 Tablet as it may increase dizziness.

Drug-Disease Interaction: Azoran 25 Tablet may cause interactions with disease conditions such as leukopenia (low levels of white blood cells), infections, have any unusual bleeding or bruising liver, and kidney dysfunction.

Drug-Drug Interactions Checker List

• TACROLIMUS
• ALLOPURINOL
• BENAZEPRIL
• CAPTOPRIL
• ENALAPRIL
• FOSINOPRIL
• LISINOPRIL
• PERINDOPRIL
• RAMIPRIL
• WARFARIN
• PHENPROCOUMON
• INFLIXIMAB
• CIMETIDINE
• MESALAZINE
• SULFASALAZINE
• FUROSEMIDE
• TRIMETHOPRIM+SULFAMETHOXAZOLE
• INDOMETHACIN
• TUBOCURARINE
• PANCURONIUM
• SUCCINYLCHOLINE

Habit Forming

No

Diet & Lifestyle Advise

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
• Acupuncture, massage, and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
• Avoid smoking and alcohol consumption.

Special Advise

• Use sunscreen while taking Azoran 25 Tablet , as it can make your skin more sensitive to sunlight and may cause skin cancer.
• Long-term use of Azoran 25 Tablet may increase your risk of developing cancers like blood cancer, skin cancer and immune system cancer (lymphoma).

Patients Concern

Disease/Condition Glossary

Rheumatoid arthritis: It is an autoimmune disease (the body’s immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Kidney transplant rejection: When you get a new kidney transplanted to your body, your body recognizes it as a foreign element and tries to attack, and reject it because it is not originally part of your body. So, immunosuppressant drugs like Azathioprine are given to such patients to suppress their immune system to attack a newly transplanted kidney. The ultimate goal is to adjust immunosuppressants to prevent rejection and minimize any side effects of the drugs.