Defcort Oral Suspension 30 ml

Defcort Oral Suspension is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn’t work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy.

Defcort Oral Suspension is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Defcort Oral Suspension binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Defcort Oral Suspension class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Defcort Oral Suspension makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Defcort Oral Suspension is available in both oral tablet and suspension dosage forms. The tablet form of Defcort Oral Suspension can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Defcort Oral Suspension can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Defcort Oral Suspension based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defcort Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Defcort Oral Suspension, please inform your doctor that you are allergic (hypersensitive) to Defcort Oral Suspension. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors’ consultation is required as Defcort Oral Suspension is not safe to use during pregnancy.

Treatment of Duchenne muscular dystrophy (DMD).

Defcort Oral Suspension is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Defcort Oral Suspension is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body.

Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

Store in a cool and dry place away from sunlight

Most of the side effects of Defcort Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Defcort Oral Suspension.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Defcort Oral Suspension. Before taking Defcort Oral Suspension for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions.

Drug-Drug interaction: Defcort Oral Suspension interact with anti-tuberculosis (anti TB) drugs like rifampicin, rifabutin, pain-relieving drugs like carbamazepine, Anti-seizure drugs like phenobarbitone, phenytoin & pyrimidine & antifungal like ketoconazole.

Drug-Food interaction: Not advised to be taken with grapefruit or its juice.

Drug-Disease interaction:  Care should be exercised when Defcort Oral Suspension is administered in patients with diabetes, cataracts, Thyroidism, blood pressure, kidney diseases, glaucoma & herpes.

 

• RIFAMPICIN
• RIFABUTIN
• CARBAMAZEPINE
• PHENOBARBITONE
• PHENYTOIN
• PRIMIDONE

No

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient’s immune system & thus proper care is to be taken.

 

• While taking Defcort Oral Suspension and for at least 4-6 weeks before you start taking it. If you are taking Defcort Oral Suspension, so do not receive a ‘live’ vaccine or you could develop a serious infection.
• Do not eat grapefruit or drink grapefruit juice while taking this medication as grapefruit has interaction with Defcort Oral Suspension.
• Regular eye check-ups, bone mineral test and liver function test is suggested while using Defcort Oral Suspension.

Autoimmune disease: This is a group of disorders in which the immune system doesn’t work properly due to various genetic & environmental reasons that start attacking normal cells, producing various chemicals resulting in unwanted and hazardous effects in patients. The overactive immune system leads to various symptoms that affect day-to-day life and promote diseases like arthritis and muscular weakness. The immune system can also damage the organ which has been transplanted to the patient from another person due to having different blood groups/antigens of the donor patient’s organ. The immune system considers it a foreign, harmful body, leading to complications after transplanting an organ like a kidney, liver, or heart.