USES AND BENIFITS

Ketomoon K5 15GM cream is combination of medicines used to treat skin infections caused by fungus and bacteria and certain yeasts. It is used to treat infections caused by Epidermophyton floccosum, Trichophyton spp., and Microsporum spp. These infections caused could be infection of feet, ringworm infection, or infection in groin and buttocks. It is used for the topical treatment of tinea corporis, tinea cruris and tinea pedis and in the treatment of cutaneous candidiasis, seborrheic dermatitis and scalp psoriasis, characterised by symptoms such as red, scaly, itchy patches of skin on the scalp and persistent dandruff. This cream is also used in the treatment of cryptococcal infection and infections caused by Blastomyces, Aspergillus, histoplasma. However, the uses of this cream mentioned here are not exhaustive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

Composition

The active ingredients of Ketomoon K5 15GM cream are Clobetasol propionate (0.5Mg), Gentamycin (1Mg), Iodochlorhydroxyquinoline (10Mg), Ketoconazole (20Mg) and Tolnaftate (10Mg)

Mechanism of Action of Drugs

Clobetasol propionate is a steroid which works by blocking the production of prostaglandins (chemical messengers) that make skin red, swollen and itchy. Gentamicin, a broad-spectrum antibiotic involves in inhibition of bacterial protein synthesis by binding to 30S ribosomes, eventually killing the bacteria. Iodochlorhydroxyquinoline is an antibiotic that kills bacteria and fungus by damaging the DNA.
Ketoconazole and Tolnaftate are anti-fungal drugs that changes the permeability of the cell wall of the fungal cells and prevents their growth. It binds to the phospholipids of the membrane and inhibits the fungal CYP450 activity, thereby decreasing ergosterol biosynthesis that are essential for the development of the cell membrane. This results in the death of cells due to the loss of intracellular sections.

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using Ketomoon K5 cream.

• Hypersensitivity to any of the ingredients used in the cream.
• Patients with ocular lesions
• Tuberculosis of skin

Caution:10

• Perforated tympanic membrane & broken skin
• Children less than 2 years of age
• Avoid contact with middle ear, eyes, meninges, brain

Side and Adverse Effects

The following side effects may or may not occur during the usage of Ketomoon K5 cream. It is usually well tolerated when used in the prescribed dosage guidelines. More common ones include: